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Index > Protein center > PRNP(Gene name) > Chicken
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  • PRNP (Gene name),
  • Major prion protein homolog (Protein name ),  PRIO_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    PRNP(PRN-P);
    Protein name:
    Major prion protein homolog;
    Alternative:
    Acetylcholine receptor-inducing activity(ARIA);65-21 protein;PR-LP;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Stimulates the synthesis of acetylcholine receptors in cultured chicken myotubes. May serve normally to regulate the chemoreceptor number at the neuromuscular junction and perhaps in the central nervous system as well.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    273
    Sequence:
    50:
    MARLLTTCCL | LALLLAACTD | VALSKKGKGK | PSGGGWGAGS | HRQPSYPRQP | 
    100:
    GYPHNPGYPH | NPGYPHNPGY | PHNPGYPHNP | GYPQNPGYPH | NPGYPGWGQG | 
    150:
    YNPSSGGSYH | NQKPWKPPKT | NFKHVAGAAA | AGAVVGGLGG | YAMGRVMSGM | 
    200:
    NYHFDSPDEY | RWWSENSARY | PNRVYYRDYS | SPVPQDVFVA | DCFNITVTEY | 
    250:
    SIGPAAKKNT | SEAVAAANQT | EVEMENKVVT | KVIREMCVQQ | YREYRLASGI | 
    273:
    QLHPADTWLA | VLLLLLTTLF | AMH
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345h
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    96T
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    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345m
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    96T
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    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345c
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    96T
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    ELISA Kit for Chicken Major prion protein homolog
    MSDS:
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    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345r
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    96T
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    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345b
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    96T
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    ELISA Kit for Chicken Major prion protein homolog
    MSDS:
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    ELISA Kit for Chicken Major prion protein homolog
    Cat.:
    E9345p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Major prion protein homolog
    Cat.:
    U9345h
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    Packing:
    96T
    CLIA Kit for Chicken Major prion protein homolog
    Cat.:
    U9345r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Major prion protein homolog
    Cat.:
    U9345m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Major prion protein homolog
    Cat.:
    U9345b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Major prion protein homolog
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Major prion protein homolog
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Major prion protein homolog
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Major prion protein homolog
    Cat.:
    U9345p
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    Packing:
    96T
    Polyclonal Antibody for Chicken Major prion protein homolog
    Cat.:
    P9345Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Polyclonal Antibody for Chicken Major prion protein homolog
    Cat.:
    P9345Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Monoclonal Antibody for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog
    Protein for Chicken Major prion protein homolog

    R&D Technical Data

           12% SDS-PAGE Analysis

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤5.6%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤10.6%

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    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-106

    Plasma

    98

    92-108

     

     

     

     

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    Linearity

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    93-102%

    92-103%

    95-105%

    92-107%

    EDTA plasma(n=5)

    88-96%

    93-101%

    94-102%

    95-106%

    heparin plasma(n=5)

    93-104%

     

    94-105%

    101-106%

    95-109%

     

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "A prion-like protein from chicken brain copurifies with an acetylcholine receptor-inducing activity."
      Harris D.A. , Falls D.L. , Johnson F.A. , Fischbach G.D.
      Proc. Natl. Acad. Sci. U.S.A.88:7664-7668(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 25-51
      tissue: Brain.
    3. 3.
      "Mr 42,000 ARIA: a protein that may regulate the accumulation of acetylcholine receptors at developing chick neuromuscular junctions."
      Falls D.L. , Harris D.A. , Johnson F.A. , Morgan M.M. , Corfas G. , Fischbach G.D.
      Cold Spring Harb. Symp. Quant. Biol.55:397-406(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    4. 4.
      "Prion protein NMR structures of chickens, turtles, and frogs."
      Calzolai L. , Lysek D.A. , Perez D.R. , Guentert P. , Wuethrich K.
      Proc. Natl. Acad. Sci. U.S.A.102:651-655(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 134-248
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